Current research projects

Current Projects

There are currently 12 projects in our active research programme in addition to the MRF Meningococcus Genome Library, an ongoing research resource that was started with MRF funds.

Since the charity was founded in 1989, we have awarded 147 research grants. 

The total value of our investment in vital scientific research is over £18.6 million.


Study to evaluate prevention of meningococcal carriage in teenagers (SPIT)

University of Bristol, University of Cambridge UK

Understanding whether the MenB vaccine has an effect on carriage in teenagers

*New project for September 2016*

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Are meningococci more abundant in the throats of teenagers with influenza or other common wintertime viruses?

University of Bristol, PHE Bristol, UK, Oxford University

Are people with wintertime viral infections more likely to carry high numbers of meningococcal bacteria and therefore be more infectious?

*New project for 2016*

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Study of the duration of protection after mass vaccination with a new vaccine against epidemic meningitis in the general population of Burkina Faso, a country of the African meningitis belt

Agence de Médecine Préventive, Burkina Faso

Investigating how long protection lasts after vaccination by taking blood samples from children and adults and measuring levels of immunity.

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Investigating transmission of GBS to newborn babies in Malawi

Malawi-Liverpool-Wellcome Trust Programme, Malawi

Using state-of the art genetic fingerprinting techniques to investigate the relationship between GBS bacteria carried by mothers and those causing severe GBS disease in Malawi.

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Assessing the potential benefits of GBS vaccines

University of Cambridge, UK

Evaluating the potential costs and benefits of introducing a GBS (Group B streptococcal) vaccine in the UK. GBS is the leading cause of bacterial meningitis in newborn babies

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Understanding meningococcal disease by simultaneously studying genetic blueprints of patients and the meningococci causing their illness

Public Health England, London, UK; University of Oxford, UK

Linking the MRF Meningococcal Genome Library and the 100k genomes project

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GBS Genome Library

Academic Medical Research Center, Amsterdam, The Netherlands

An online library of the genetic blueprint of Group B streptococcal bacteria

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Vaccinating expectant mothers against MenA

Medical Research Council Unit, The Gambia; Public Health England, Manchester, UK

Protecting newborn infants from meningococcal A infection and meningitis

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Investigating how people value health benefits from childhood vaccination

University of Bristol; University of Cambridge; University of Birmingham

Informing vaccine policy in the future

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Determining whether MenB vaccines can prevent a particular meningococcal strain from causing disease

University of Leicester, UK

Evaluating MenB vaccines

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Prevention and treatment

Improving understanding of meningococcal disease in Scotland by linking the genetic blueprint of the bug to information about the patient

Health Protection Scotland, Glasgow, UK

Pioneering new MRF-supported genome sequencing research backed by Health Protection Scotland to improve prevention, diagnosis and treatment of meningitis

*New project for 2016*

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An in-depth study of the genes involved with the susceptibility and the severity of meningococcal disease in children

Imperial College London, UK

Exploring the biological and functional role of genes in susceptibility and outcome of meningitis and septicaemia.

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Using new genomic techniques to identify the causes of meningitis in UK children.

University of Oxford, UK

Improving detection and treatment.

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Defining meningitis in UK children in the conjugate vaccine era

University of Oxford, UK

Describing the symptoms, clinical signs and laboratory results of all children with meningitis. Investigating differences between children with bacterial and viral meningitis to determine how to differentiate these two groups.

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Improving meningitis survival among people living with AIDS in Tanzania

Ifakara Health Institute, Tanzania

Maximising meningitis detection and prompt referral in a rural district

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MRF funds pioneering new research that could eventually help stop loss of limbs from meningitis

Instituit Necker, Paris, France

Understanding meningococcus-induced blood clotting - Working towards new therapeutics for purpura fulminans

*New project for 2016*

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Page last updated 19.05.16