Conference 2013

Meningitis and septicaemia in children and adults 2013


Click on the name of the presentation to find out more about the speaker, read the abstract and, where available, download the presentation.





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Day one

Burden of Illness

Chair: Dr Mary Ramsay
Public Health England, London
 
Current epidemiology of meningococcal disease in the UK and Europe, including issues for surveillance relating to a MenB vaccine costs of meningitis
Dr Shamez Ladhani, Public Health England, London
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A parent’s experience of meningococcal disease
Karen Crockatt, Member and Ambassador of Meningitis Research Foundation
New studies of QALY loss in patients and  carers; family impact of meningitis and septicaemia
Dr Hareth Al-Janabi, University of Birmingham, University of Bristol
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Health economic evaluation for public health decisions involving severe diseases which primarily affect young children – problems and possible solutions cost of meningitis
Prof Philippe Beutels, University of Antwerp, Belgium

Advances from research: implications for prevention & treatment

Chair: Prof Nigel Klein
Great Ormond Street Children’s Hospital and Institute of Child Health, University College London
Factor H binding protein and vaccine approachesd
Prof Christoph Tang, University of Oxford
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The emerging picture of host genetic control of susceptibility and outcome in meningococcal disease - evidence from multiple GWAS
Prof Michael Levin, St Mary’s Hospital, Imperial College London
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Towards global genomic disease surveillance; the Meningitis Research Foundation (MRF) Meningococcus Genome Library and beyond
Prof Martin Maiden, University of Oxford
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Group B streptococcal infection & neonatal meningitis

Chair: Prof Paul Heath
St George’s University of London
Neonatal meningitis in the UK
Dr Ifeanyichukwu Okike, St George’s University of London
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Novartis Group B Streptococcus vaccine programme
Dr Karen Slobod, Novartis Global Development, USA
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Tackling meningitis in Africa

Chair: Prof Brian Greenwood
London School of Hygiene and Tropical Medicine
Confronting cryptococcal meningitis in Africa
Prof Tom Harrison, St George’s University London
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The impact of MenAfriVac on serogroup A invasive meningococcal disease and carriage in Chad
Dr Doumagoum Moto Daugla, Centre de Support en Santé Internationale, Chad
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Elimination of meningitis A epidemics in Africa; MenAfriVac future plans
Dr Marie-Pierre Préziosi, Meningitis Vaccine Project (WHO/PATH), Switzerland
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Implementing an mHealth triage intervention for health care workers at primary health centres in urban Blantyre, Malawi – a pilot study
Dr Nicola Desmond, Malawi-Liverpool-Wellcome Clinical Research Programme, Malawi

Day two

Novartis Satellite Breakfast Session

Confidence in numbers: the evidence base for assessing the public health impact of vaccines against invasive meningococcal diseases

Chair: Emeritus Prof Richard Moxon, University of Oxford

Measuring disease burden and estimating vaccine impact
Dr Jamie Findlow, Public Health England, Manchester
Challenges to quantifying the severity of meningococcal disease
Dr Simon Nadel, St Mary’s Hospital, London
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Current issues in clinical management

Chair: Professor Robert Heyderman
Malawi-Liverpool-Wellcome Trust
Debate on aggressive vs restricted fluid resuscitation in childhood sepsis
Prof Michael Levin & Dr David Inwald, St Mary’s Hospital, Imperial College London
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Round up of new developments in clinical management of meningitis or sepsis in paediatric and adult settings
Dr Simon Nadel, St Mary’s Hospital, London
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Management of sepsis and meningitis in developing countries
Dr Louisa Pollock, Wellcome Trust Tropical Centre, Liverpool

Preventing pneumococcal disease

Chair: Prof Ray Borrow
Public Health England Vaccine Evaluation Unit, Manchester
Current epidemiology and summary of vaccines in development; the need for higher-valent and alternative vaccines
Prof David Goldblatt, Institute of Child Health, London
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Pneumococcal conjugate vaccine implementation in Africa with a focus on Kenya
Prof Anthony Scott, London School of Hygiene and Tropical Medicine

Poster Presentations

Chair: Prof David Lalloo
Liverpool School of Tropical Medicine
E17 Quality of life changes in children diagnosed with group B meningococcal disease in months following illness
Dr Iain Kennedy, Public Health England, London
V48 Safety, Tolerability, and Immunogenicity of an Investigational Meningococcal Serogroup B Bivalent rLP2086 Vaccine in Healthy Adolescents When Administered in Regimens of 2 or 3 Doses in Healthy Subjects aged 11 to 18 Years
Dr John Perez, Pfizer Vaccine Research, Collegeville, PA, USA
P2 Temperature triggers immune evasion by Neisseria meningitidis
Dorothea Hill, University of Oxford
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V43 Impact of Quadrivalent Conjugate (MenACWY- CRM) and Serogroup B (4CMenB) Meningococcal Vaccines on Meningococcal Carriage in English University Students
Prof Robert Read, University of Southampton
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Prevention of meningitis and septicaemia

Chair: Prof Andrew Pollard
University of Oxford
Current issues with meningococcal vaccine programmes in the UK
Dr Mary Ramsay, Public Health England, London
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Current issues with meningococcal vaccine programmes in the Netherlands
Dr Fiona van der Klis, Public Health Institute of the Netherlands (RIVM)
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Carriage studies – what do they add? Human bacterial challenge experiments as an alternative
Dr Caroline Trotter, University of Cambridge;
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Prof Stephen Gordon, Liverpool School of Tropical Medicine
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Future prospects for prevention of meningococcal disease

Chair: Prof Ian Feavers
National Institute for Biological Standards and Control, Potters Bar
Non-routine use of meningococcal vaccines in outbreaks and for individuals with clinical risk factors
Dr Matthew Snape, University of Oxford
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Meningococcal vaccines – have we been asking the wrong questions?
Prof Adam Finn, University of Bristol
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Immunisation against serogroup B meningococcal disease - hopes and fears
Panel discussion moderated by Prof Paul Heath
Panellists: Prof Adam Finn, University of Bristol, Dr Simon Nadel, Prof Robert Read, Dr Matthew Snape and Dr Caroline Trotter
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Meningitis and Septicaemia in Children and Adults 2013's major sponsors are: Conference sponsors

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