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meningitis & septicaemia can kill in hours!

People who are faced with meningitis and septicaemia have to act fast to help save a life.

Scientific Version

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The role of the microcirculation in the pathophysiology of meningococcal disease

Alderhey Children's Hospital, Liverpool, UK, Institute of Child Health, London, UK, Liverpool University, Liverpool, UK

Meningococcal disease (MCD) may present with severe sepsis, which impairs the circulation. Currently macro-circulatory variables (pulse, blood pressure, central venous pressure) are used to...

Understanding cross-protective natural immunity conferred by Neisseria lactamica to develop meningococcal vaccines.

Health Protection Agency, Salisbury, UK, Imperial College, London, UK, National Institute for Biological Standards and Control, Hertfordshire, UK

The purpose of this project is to understand the basis of natural anti-meningococcal immunity that is conferred by infection with N. lactamica.

Long-term outcome in adults with acute bacterial meningitis and the impact of dexamethasone treatment.

University of Amsterdam, Amsterdam, The Netherlands

Bacterial meningitis remains a disease with high mortality and morbidity rates.

Randomised trial of glycerol adjuvant therapy in adult bacterial meningitis in Malawi.

Liverpool School of Tropical Medicine, Liverpool, UK, University of Malawi, Blantyre, Malawi

Malawi has a high incidence of bacterial meningitis among adults. Currently, mortality exceeds 50%. More effective locally appropriate treatments are an urgent priority.

A cross-sectional study of nasopharyngeal carriage in teenagers prior to vaccination with New Zealand OMV meningococcal B vaccine.

University of Auckland, Auckland, New Zealand

This study is aiming to determine the impact of a serogroup B outer membrane vesicle vaccine on meningococcal carriage rates in New Zealand, and specifically the epidemic strain (with a B:P1.7b,4 Por...

Identification of the genes controlling meningococcal disease susceptibility and severity.

Imperial College, London, UK

There is now clear evidence that genetic factors play an important role in determining susceptibility, clinical course and outcome of infectious diseases including meningococcal sepsis.

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