Alderhey Children's Hospital, Liverpool, UK, Institute of Child Health, London, UK, Liverpool University, Liverpool, UK
Meningococcal disease (MCD) may present with severe sepsis, which impairs the circulation. Currently macro-circulatory variables (pulse, blood pressure, central venous pressure) are used to...
Health Protection Agency, Salisbury, UK, Imperial College, London, UK, National Institute for Biological Standards and Control, Hertfordshire, UK
The purpose of this project is to understand the basis of natural anti-meningococcal immunity that is conferred by infection with N. lactamica.
University of Amsterdam, Amsterdam, The Netherlands
Bacterial meningitis remains a disease with high mortality and morbidity rates.
Liverpool School of Tropical Medicine, Liverpool, UK, University of Malawi, Blantyre, Malawi
Malawi has a high incidence of bacterial meningitis among adults. Currently, mortality exceeds 50%. More effective locally appropriate treatments are an urgent priority.
University of Auckland, Auckland, New Zealand
This study is aiming to determine the impact of a serogroup B outer membrane vesicle vaccine on meningococcal carriage rates in New Zealand, and specifically the epidemic strain (with a B:P1.7b,4 Por...
Imperial College, London, UK
There is now clear evidence that genetic factors play an important role in determining susceptibility, clinical course and outcome of infectious diseases including meningococcal sepsis.