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meningitis & septicaemia can kill in hours!

People who are faced with meningitis and septicaemia have to act fast to help save a life.

Scientific Version


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CD40 ligation for enhancement of immune responses to capsular polysaccharides

University of Sheffield, Sheffield, UK

Strong antibody responses against capsular polysaccharides normally provide protection against diseases caused by encapsulated bacteria.


Characterisation of natural group B meningococcal proteins expressed in vivo: a proteome analysis

University of Aberdeen, Aberdeen, UK

Serogroup B meningococcal infections account for over 63% of meningococcal infections in the United Kingdom.


Identification and characterisation of iron-regulated genes in Streptococcus pneumoniae by representational difference analysis of cDNA

University of Sussex, Brighton, UK

Streptococcus pneumoniae (the pneumococcus), a major cause of bacterial meningitis, is associated with high mortality and morbidity.


Improved non-culture diagnosis and case ascertainment of bacterial and viral meningitis including septicaemia

PHLS Meningococcal Reference Unit, Manchester, UK

Non-culture diagnosis of meningitis by PCR is increasingly important and has had a major impact on the confirmation and improved case ascertainment for meningococcal infection.


Polymerase chain reaction (PCR) and 165rRNA sequencing in the detection of non-culturable etiological agents of culture-negative meningitis: a pilot study

Belfast City Hospital, Belfast, UK

The inability to detect agents in CSF and in blood cultures may be attributed to the presence of organisms, which are unusual, extremely fastidious and which may not be cultured in vitro.


The adolescent peak in meningococcal disease: An integrated social, biological and psychological investigation

Institute of Child Health, London, UK, Great Ormond Street Hospital, London, UK

Meningococcal disease (MD) has a bimodal distribution peaking in infancy and adolescence.


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David Brennan
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