University of Sheffield, Sheffield, UK
Strong antibody responses against capsular polysaccharides normally provide protection against diseases caused by encapsulated bacteria.
University of Aberdeen, Aberdeen, UK
Serogroup B meningococcal infections account for over 63% of meningococcal infections in the United Kingdom.
University of Sussex, Brighton, UK
Streptococcus pneumoniae (the pneumococcus), a major cause of bacterial meningitis, is associated with high mortality and morbidity.
PHLS Meningococcal Reference Unit, Manchester, UK
Non-culture diagnosis of meningitis by PCR is increasingly important and has had a major impact on the confirmation and improved case ascertainment for meningococcal infection.
Belfast City Hospital, Belfast, UK
The inability to detect agents in CSF and in blood cultures may be attributed to the presence of organisms, which are unusual, extremely fastidious and which may not be cultured in vitro.
Institute of Child Health, London, UK, Great Ormond Street Hospital, London, UK
Meningococcal disease (MD) has a bimodal distribution peaking in infancy and adolescence.