Vaccine potential and functional attributes of TspA, a potent CD4+ T-cell and B-cell stimulating neisserial protein
Research archive
- University of Nottingham, Nottingham, UK
- Researchers:
Ala'Aldeen DA
- Project Number: 9931.0
- Category: Prevention
- Duration: 2000 - 2004
- Start Date: 01 January 2000
- Type: Scientific
Results from this study have been published in scientific journals as follows:
Hadi HA, Wooldridge KG, Robinson K, Ala'Aldeen DA.
Identification and characterization of App: an immunogenic autotransporter protein of Neisseria meningitidis.
Mol Microbiol 2001 Aug;41(3):611-23.
http://www.blackwell-synergy.com/doi/abs/10.1046/j.1365-2958.2001.02516.x
Robinson K, Neal KR, Howard C, Stockton J, Atkinson K, Scarth E, Moran J, Robins A, Todd I, Kaczmarski E, Gray S, Ala'Aldeen DA.
Characterization of humoral and cellular immune responses elicited by meningococcal carriage.
Infect Immun 2002 Mar;70(3):1301-9.
http://iai.asm.org/cgi/reprint/70/3/1301.pdf
Robinson K, Wooldridge KG, Wells DB, Hasan A, Todd I, Robins A, James R, Ala'Aldeen DA.
T-cell-stimulating protein A elicits immune responses during meningococcal carriage and human disease.
Infect Immun 2005 Aug;73(8):4684-93.
http://iai.asm.org/cgi/reprint/73/8/4684.pdf
Oldfield NJ, Bland SJ, Taraktsoglou M, Dos Ramos FJ, Robinson K, Wooldridge KG, Ala'Aldeen DA,.
T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells.
Cell Microbiol 2007 Feb;9(2):463-78. Epub 2006 Sep 11.
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1462-5822.2006.00803.x