Development of a novel test for bacterial meningitis and septicaemia
Research archive
- Queen's Medical Centre, Nottingham, UK
- Project Number: 9610.0
- Category: Detection
- Duration: 1997
- Start Date: 01 January 2007
- Type: Lay summary
- View scientific version
In this project a simple colour change is being used to speed up the interpretation of PCR results. Researchers aim to make the test so easy to read and user-friendly that it can be adopted in regional laboratories which have PCR capability. It aims to reduce the time required for diagnosis, which could provide invaluable information to doctors treating patients with suspected meningitis and septicaemia.
Results from this study have been published in scientific journals as follows:
Seward RJ, Towner KJ.
Use of an automated DNA analysis system (DARAS) for sequence-specific recognition of Neisseria meningitidis DNA. Clin Microbiol Infect 2000 Jan;6(1):29-33.
http://www.blackwell-synergy.com/doi/abs/10.1046/j.1469-0691.2000.00010.x
Seward RJ, Towner KJ.
Evaluation of a PCR-immunoassay technique for detection of Neisseria meningitidis in cerebrospinal fluid and peripheral blood.
J Med Microbiol 2000 May;49(5):451-6.
http://jmm.sgmjournals.org/cgi/reprint/49/5/451.pdf