Completed projects

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Molecular mimics of meningococcal lipo-oligosaccharides as vaccine candidates

Royal Free Hospital, London, UK

Despite encouraging progress in the development of glycoconjugate vaccines against serogroup A and C meningococci, the development of an effective vaccine against serogroup B organisms remains a...

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Macrophage migration inhibitory factor, high mobility group 1 and macrophage inhibitory cytokines in meningococcal disease in children

Alderhey Children's Hospital, Liverpool, UK

Despite more intensive medical management and the recent anti-endotoxin and cytokine therapies the mortality and morbidity of patients with meningococcal disease (MCD) remains significant.

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The preterm infant's immune response to an acellular pertussis-Hib and meningitis C conjugate vaccine given together

Portsmouth Hospitals NHS Trust, Portsmouth, UK

100 infants born at 31 weeks gestation or less will be immunised with a combined three component acellular pertussis-HIB vaccine at the same time as a meningitis C conjugate vaccine at 2, 3 and 4...

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Why is the death rate so high amongst adults with meningitis in Africa?

Elizabeth Central Hospital & Department of Microbiology, Blantyre, Malawi, Liverpool School of Tropical Medicine, Liverpool, UK

Improving the outlook for adults in Africa

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Impact of pneumococcal conjugate vaccine on pneumococcal disease prevalence and genetics in the UK

HPA Centre for Infections, London, UK

Monitoring the effect of pneumococcal vaccine

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Does HIV infection boost carriage of Group B streptococcus bacteria in pregnant women and increase the risk of infection in new born babies?

Elizabeth Central Hospital & Department of Microbiology, Blantyre, Malawi, London School of Hygiene & Tropical Medicine, London, UK

HIV infection and GBS

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