Dr Sharples studied medicine at St Mary’s Hospital London. She trained in paediatric neurology in Great Ormond Street Hospital, Oxford and Newcastle where she was an Action Research Training Fellow and First Assistant in Paediatric Neuroscience. Her PhD, which described the relationship between clinical outcome and cerebral metabolism in children with severe traumatic brain injury, was awarded the Michael Blacow prize of the Royal College of Paediatrics and Child Health and the Ronnie McKeith Prize of the British Paediatric Neurology Association.
Dr Sharples is a Consultant Paediatric Neurologist at the Bristol Royal Hospital for Sick Children and a senior lecturer in the Institute of Child Health at Bristol. As well as leading the paediatric neuro-rehabilitation service at Frenchay Hospital, she heads a clinical and experimental program of research, funded by grants from national bodies including the Department of Health, the British Brain and Spine Foundation, the Royal College of Surgeons, and Cancer and Leukaemia in Childhood.